Objective
Brain tumors are poorly understood. The purpose of this research is to examine whether lifestyle plays a role in brain tumor development. The study will also investigate whether inherited susceptibility plays a role. By gaining a better understanding of these factors, the investigators hope to learn how to prevent brain tumors in the future.

Design
This is a case-control investigation. Persons affected with a brain tumor (the ‘cases’) are compared to persons without a brain tumor (the ‘controls’). Cases eligible for the study are persons at least 18 years of age who were recently diagnosed with a brain tumor. Controls must also be at least 18 years of age and should not have a personal history of brain tumors. Controls may be friends or family members of the cases (eg. persons with brain tumors) or they may be randomly selected from the community.

Protocol
Those enrolled in the study will complete an interview on diet and lifestyle. They will also be asked to provide saliva and other samples that enable the investigators to measure trace elements in diet. All procedures can be performed in the clinic or through the mail, and will take no more than 1-2 hours to complete.

History of the Study
December
March
March
January
March
June
2004
2004
2005
2006
2007
2007
Enrollment initiated at Vanderbilt University in Nashville, TN
Kentuckiana Cancer Institute in Louisville, KY joins the study
Emory University in Atlanta, GA joins the study
University of Alabama at Birmingham joins the study
Moffitt Cancer Center in Tampa, FL joins the study
Study receives funding from the National Cancer Institute
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